Benzon Symposium No. 57

Acute Pain - Pathophysiology and Risk Factors for Chronification

 

Copenhagen, October 4-7, 2010

  Organizing committee:
 Henrik Kehlet (Copenhagen), Troels Staehelin Jensen (Aarhus), Arne Svejgaard (Copenhagen) & 
Povl Krogsgaard-Larsen (Copenhagen)

 

CONFIRMED INVITED SPEAKERS

Aasvang, Eske Kvanner (Denmark)

Jensen, Troels Staehelin (Denmark)

Arendt-Nielsen, Lars (Denmark)

Kehlet, Henrik (Denmark)

Baron, Ralf (Germany)

Kress, Michaela (Austria)

Brennan, Timothy J. (USA)

Macrae, William A. (United Kingdom)

Basbaum, Allan (USA)

Maixner, William (USA)

Dickenson, Anthony (United Kingdom)

Mayer, Emeran A (USA)

Dworkin, Robert H. (USA)

McMahon, Steve (United Kingdom)

Eisenach, James (USA)

Olesen, Jes (Denmark)

Fillingim, Roger (USA)

Raja, Srinivasa (USA)

Finnerup, Nanna Brix (Denmark)

Salter, Michael W (Canada)

Gebhart,  Gerald F (USA)

Schmelz, Martin (Germany)

Gilron, Ian (Canada)

Tracey, Irene (United Kingdom)

Haythornwaite, Jennifer A. (USA)

Treede, Rolf-Detlef (Germany)

The Benzon Symposia are international conferences on front line research in medical, pharmaceutical, and related sciences funded by the Alfred Benzon Foundation. The idea of the Symposium is to bring together both young and experienced scientists interested in acute pain physiology and treatment and risk factors for transition into a chronic pain state. The 57th Benzon Symposium will provide a very comprehensive approach to the subject based upon updated knowledge on the pathophysiology of acute pain, a thorough discussion on pre-, intra- and post injury risk factors and strategies for prevention and treatment based upon specific lectures within well-defined surgeries and diseases. Symposium No. 57 will feature lectures by 26 invited speakers as well as posters and oral poster-presentations selected from submitted abstracts.

Attendance will be limited to 150 participants.

The symposium will take place at Hotel Skt. Petri, a modern designer hotel located in the heart of Copenhagen. All participants will stay at the Hotel Skt. Petri. We look forward to seeing you in Copenhagen 

The organizing committee

 

DEADLINES

Participants are selected primarily on the basis of abstracts submitted using the Abstract Form to be downloaded from this site. 
Abstract deadline, May 1, 2010 
Registration and payment deadline, August 1, 2010

SYNOPSIS

The pathogenic mechanisms and treatment strategies for chronic pain states are still largely unknown but may be facilitated by increased knowledge on the transition from acute pain states into a persistent pain state. In this context, elective surgery may represent an ideal model due to the possibility of assessing patients before and after the injury regarding pre-, intra- and postoperative risk factors. The aim of this symposium is to study the transition from various surgical and non-surgical acute pain states into a persistent pain state in order to outline strategies for prevention and treatment.

PROGRAMME LAYOUT

Monday, October 4 - Thursday, October 7, 2010
Each day (9 AM - 6 PM) will include:
· 6-8 Lectures
· 3-6 Oral poster presentations
· 1 x Poster session
· 1 x Lunch
· 2 x Coffee break

Session I Basic Studies
Session II Clinical Studies
Session III Risk Factors in Specific Surgeries and Diseases
Session IV Strategies for Treatment and Prevention

Reception Monday evening
Banquet Wednesday evening

 

APPLICATION FOR PARTICIPATION  

Participants are selected primarily on the basis of abstracts submitted using the Abstract Form to be downloaded from this site.
Application for participation without a poster presentation may be submitted before May 1 but only considered after August 1, 2010 on a first come, first served basis.

Abstracts:

Abstracts are to be submitted via E-mail: benzon@post1.tele.dk before May 1, 2010.

Abstract Form with instructions for the preparation, and an Example can be downloaded here.

Approved abstracts will be presented as posters and/or in oral presentations. Around June 1, 2010 you will be informed about acceptance and type of presentation.

Registration:

Scientists whose abstracts have been approved will receive a registration form (incl. hotel reservation). Deadline for return of the registration form together with the registration fee is August 1, 2010.

Fee:

Participants: The registration fee for participants, DKK 4,500,-, covers participation in the symposium, hotel accommodation including breakfast (Sunday night-Friday morning), lunches and coffee during the conference, and the following social evening arrangements: Reception on Monday and Banquet on Wednesday.
Accompanying persons: The fee for non-participating, accompanying persons, DKK 1,500,-, covers accommodation (shared with the participant) including breakfast and social evening arrangements together with the participants. For accompanying persons only, there will be two day-time excursions which are also included in the fee.

VENUE

Accommodation and Scientific meeting:
Hotel Skt. Petri, Krystalgade 22 · 1172 Copenhagen · Denmark
Tel. +45 3345 9100 · Fax +45 3345 9110, http://www.firsthotels.dk/sktpetri

GENERAL INFORMATION

Copenhagen (Denmark's capital) was founded by Bishop Absalon in the 12th century. Its beautiful centre is rich in 17th and 18th century architecture, museums, and lively squares and pedestrian streets with plenty of restaurants, cafes, pubs, and shopping opportunities. The numerous recreational areas include the waterfront and the remains of the fortification surrounding the old city with a ring of lakes and parks including the Tivoli Gardens.
You may arrive at the very heart of Copenhagen by ferry or train or fly in to Copenhagen Airport at Kastrup, 10 km from the centre. From the airport there is a convenient direct train to the centre (Nørreport), only 5 minutes walk from the hotel.
In October, the average daily temperature is just around 10 degrees centigrade. The weather is often sunny with occasional showers.

 

FURTHER INFORMATION
Dr. Jette Buur, The Alfred Benzon Foundation
Dantes Plads 3, II.t.v. DK-1556 Copenhagen V, Denmark
Phone: +45 3962 0937; Fax: +45 3962 0933
E-mail: benzon@post1.tele.dk

TENTATIVE PROGRAMME
Opening lecture:
William A. Macrae: Chronic Pain after Surgery, how the Problem Evolved

Basic Studies:
Timothy J. Brennan: Peripheral Mechanisms of Acute and Chronic Post-injury Pain
Michael W Salter: Central Signalling Systems in Dorsal Horn Neuroplasticity
Michaela Kress: Proinflammatory Cytokines and Sphingolipids at the Crossroad between Nociceptors and the Immune System
Steve McMahon: Neurotrophic Factors in Inflammatory and Neuropathic Pain
Gerald F. Gebhart: Mechanisms of Visceral Hypersensitivity
Allan Basbaum: Specificity vs. Patterning Revised in the Generation and Control of Pain
Panel discussions on how to translate findings from experimental studies into design of clinical studies.

Clinical Studies:
Srinivasa Raja: Persistent Pain as a Sequel of Acute Pain: Epidemiology
Troels Staehelin Jensen: The Clinical Presentation of Persistent Pain
Ralf Baron: The Role of Quantitative Sensory Testing in Pain Classification
Rolf-Detlef Treede: Assessment of Sensitisation in Persistent Pain
Martin Schmelz: Structural and Functional Neuronal Changes in Chronic Pain Patients
Irene Tracey: Imaging Pathophysiological and Psychological
Changes Underpinning the Transition of Acute to Chronic Pain
Jennifer A. Haythornwaite: Psychosocial Contributions to the Chronicity of Pain
Roger Fillingim: Individual Differences in Pain Sensitivity as a Risk Factor for Chronic Pain

Risc Factors in Specific Surgeries and Diseases:
Eske Kvanner Aasvang: Herniotomy
Srinivasa Raja: Breast Surgery
Henrik Kehlet: Thoracotomy
James Eisenach: Obstetric and Gynaecologic Surgery
Robert H. Dworkin: Post-herpetic Neuralgia
Jes Olesen: Headache
William Maixner: Temporo-mandibular Syndrome
Lars Arendt-Nielsen: Muscle and Visceral Pain
Emeran A Mayer: Generalized Persistent Pain Syndromes

Strategies for Treatment and Prevention:
Nanna Brix Finnerup: Update on Existing Pharmacological Treatment in Neuropathic Pain
Anthony Dickenson: Potential new Targets in Persistent Pain: One or multiple Mechanisms ?
Timothy J. Brennan: Pre-emptive Analgesia - Fact or Fiction?
Ian Gilron: Strategies for Future Study Designs in Chronic Pain

The Way Forward:
Henrik Kehlet
Troels Staehelin Jensen
Srinivasa Raja

Closing Comments